"Real People" has no special meaning on campus that I know of. I'm assuming the signage really is doing what it says on the tin: all math/science/engineering takes place in buildings to the left, while the management, economics, and poli sci departments are all to the right. Of course, as a humanities major, I'm a bit offended that the hackers forgot that my department is to the left, not the right, but everyone forgets that MIT has humanities majors.
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Nice choice of icon, btw.